United States securities and exchange commission logo April 22, 2021 Scott Dunbar Acting Chief Executive Officer Second Sight Medical Products, Inc. 13170 Telfair Ave Sylmar, California 91342 Re: Second Sight Medical Products, Inc. Registration Statement on Form S-3 Filed April 16, 2021 File No. 333-255267 Dear Mr. Dunbar: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Alan Campbell at 202-551-4224 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Aaron A. Grunfeld, Esq.